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Heart Failure

Heart failure is a chronic condition that affects more than 26 million people globally. Heart failure with preserved ejection fraction (HFpEF), previously known as Diastolic Heart Failure (DHF), accounts for approximately 50% of all heart failure, affecting approximately 7 million people in the United States and Europe.

People with heart failure have difficulty breathing, often struggle with simple daily activities, and are frequently hospitalized. For many, these symptoms drastically reduce their quality of life.

In a healthy heart, the left ventricle (lower left chamber) relaxes to fill with blood from the left atrium (upper left chamber). Once filled, the left ventricle pumps the blood to the body.

HFpEF occurs when the left ventricle becomes stiff and does not relax normally. As a result, it cannot fill properly. Blood begins to back up, increasing pressure inside the left chambers of the heart and the lungs.

To learn more, visit www.heartfailurematters.org.