CAUTION–Investigational Device. Limited by United States Law to Investigational Use.
Assessment of Predictors of Left Atrial Volume Response to a Transcatheter InterAtrial Shunt Device (from the REDUCE LAP-HF Trial)
Hanff T., Kaye D., Hayward C., et al.
Am J Cardiol. 2019 Dec 15;124(12):1912-1917
Effects of Interatrial Shunt on Pulmonary Vascular Function in Heart Failure with Preserved Ejection Fraction
Obokata M., Reddy Y., Shah S., et al.
JACC 2019 Nov 26:74(21):2539-50
Impact of an Interatrial Shunt Device on Survival and Heart Failure Hospitalizations in Patients with Preserved Ejection Fraction
Kaye D., Petrie M., McKenzie S., et al.
ESC Heart Fail. 2019 Feb; 6(1): 62-69
One-Year Safety and Clinical Outcomes of a Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure With Preserved Ejection Fraction in the Reduce Elevated Left Atrial Pressure in Patients With Heart Failure (REDUCE LAP HF I) Trial
Shah S., Feldman T., Ricciardi M., et al.
JAMA Cardiol. 2018 Oct 1;3(10):968-977
Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure With Preserved Ejection Fraction REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure] A Phase 2, Randomized, Sham-Controlled Trial
Feldman T., Mauri L., Kahwash R., et al.
Circulation. 2018 Jan 23;137(4):364-375
One-Year Outcomes After Transcatheter Insertion of an Interatrial Shunt Device for the Management of Heart Failure With Preserved Ejection Fraction
Kaye D., Hasenfuß G., Neuzil P., et al.
Circ Heart Fail. 2016 Dec; 9(12).
Transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicenter, open label, single-arm, phase 1 trial
Hasenfuß G., Hayward C., Burkhoff D. et al.
Lancet 2016; 387: 1298–304.
Clinical Outcome of Transcatheter Treatment of Heart Failure with Preserved or Mildly Reduced Ejection Fraction Using a Novel Implant
Malek F, Neuzil P, Gustafsson F, et al.
International Journal of Cardiology 2015; 187:227–28.
Rationale and Design of the Reduce Elevated Left Atrial Pressure in Patients With Heart Failure (Reduce LAP-HF) Trial
Hasenfuβ G, Gustafsson F, Kaye D, et al.
J Card Fail 2015; 21(7): 594-600.
Effects of an Interatrial Shunt on Rest and Exercise Hemodynamics: Results of a Computer Simulation in Heart Failure
Kaye D, Shah S, Borlaug B, et al.
Journal of Cardiac Failure. 2014;20(3):212-21.
Transcatheter Treatment of Heart Failure with Preserved or Mildly Reduced Ejection Fraction Using a Novel Interatrial Implant to Lower Left Atrial Pressure
Søndergaard L, Reddy V, Kaye D, et al.
Eur J Heart Failure 2014; 16:796-801.